Electronic Resource
NEONATAL FORMULARY : DRUG USE IN PREGNANCY AND THE FIRST YEAR OF LIFE
Staff should never prescribe or administer any drug without first familiarising themselves with the way it works, the way it is handled by the body and the problems that can arise as a result of its use. Most of the essential facts relating to use in adults are summarised by the manufacturer in the ‘package insert’ or Summary of Product Characteristics (SPC). Many are also summarised in a range of reference texts such as the British National Formulary (BNF) and the BNF for Children (BNFC). However manufacturers seldom provide much information about drug handling in infancy. Although BNFC now offers more advice on dosage in childhood than can be obtained from the manufacturer’s package insert, it stresses that the use of any unlicensed medicine (or licensed medicine in an unlicensed manner) should only be undertaken by those who have also first consulted other appropriate and up-to-date literature. This edition of Neonatal Formulary aims to summarise and to provide a referenced guide to that literature. While many texts offer advice on the best dose to use in infancy – often in tabular form – very few provide much information on the idiosyncrasies associated with neonatal use. Such dosage tables can be a useful aide mémoire, but they should never be relied upon, on their own, to help the staff decide what to use when, what works best or what potential adverse effects are commonly encountered during use in infancy. Lists summarising common side effects and potential drug interactions are seldom of much help in identifying which problems are common or likely to be of clinical importance in the neonate, and access to this more detailed information is as important for the staff responsible for drug administration as it is for those prescribing treatment in the first place. Similar challenges relate to the safe use of drugs during pregnancy and lactation because standard texts (such as the BNF) offer very little information as to what is, and is not, known about use in these circumstances. Such information is available in a range of specialised reference texts (see p. 558) and Part 3 of this compendium summarises what is currently known about the use of most of the more commonly used drugs
EBK-00201 | 618.920 1/Joh-n | Perpus Pusat | Tersedia |
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