Acute gout attacks are characterized by rapid onset of excruciating pain, swelling, and inflammation. The attack is typically monoarticular, most often affecting the first metatarsophalangeal joint (podagra), and then, in order of frequency, the insteps, ankles, heels, knees, wrists, fingers, and elbows. Attacks commonly begin at night, with the patient awakening with excruciating pain. Affecte…
Basic and clinical research provides a continuous flow of biomedical information that enables practitioners to use medications more effectively and safely. The editors, authors, and publisher of this book have made every effort to ensure accuracy of information provided. However, it is the responsibility of all practitioners to assess the appropriateness of published drug therapy information, e…